Background: There is growing evidence of the importance of genetic predisposition and the …
of inflammatory bowel disease. Thus, genes involved in the regulation of inflammation are …

… The low prevalence of inflammatory bowel diseases among blacks as opposed to whites …
chronic inflammatory disease such as rheumatoid arthritis and inflammatory bowel disease are …

… have been related to a number of chronic inflammatory diseases such as multiple sclerosis
and inflammatory bowel disease (… but not with polymorphisms in the interleukin‐1beta gene. …

… genetic polymorphisms and inflammatory bowel disease … of two polymorphisms of the
interleukin-1 pathway, IL-1β-511 … and interleukin-1 receptor antagonist gene polymorphisms in …

… involved in the induction of inflammation. Its production has been linked to the severity of
several chronic inflammatory diseases, such as inflammatory bowel disease,8, 9 rheumatoid …

… Ulcerative colitis (UC) is an inflammatory bowel disease of … IL1B gene polymorphisms
in patients with inflammatory bowel … plasma interleukin-1 receptor antagonist, respectively. …

… in the pathogenesis of inflammatory bowel disease (IBD). … osteoclast activity while interleukin
1 receptor antagonist (IL-… whether genetic polymorphisms in the IL1Band IL1RN genes …

… of inflammatory diseases including inflammatory bowel … (IL-1Ra) genes in inflammatory bowel
disease. Clin Exp Immunol 102(… of leptin in normal and interleukin-1beta-treated male rats. …

… shown that polymorphisms on interleukin-1 receptor-associated … Given that anakinra, an
interleukin-1 receptor antagonist, … diseases, our results provided evidence for IL-1R antagonist …

… Background:: Polymorphisms in the interleukin 1β gene (IL-1B-31T/C and IL-1B-511C/T
single nucleotide changes) and in the interleukin 1 receptor anatagonist gene (IL-1RN2 variable …